Beilstein J. Org. Chem.2020,16, 502–508, doi:10.3762/bjoc.16.45
. Moreover, the reaction of α-bromocarbonyl compound 2 and an alkyne 4 possessing a carboxamide moiety undergoes tandem alkyl radical addition/C–H coupling to produce indolinone derivative 5.
Keywords: copper catalyst; 1,3-enyne; functionalizedquaternarycarbon; indolinone; tandem alkyl radical addition
related coupling reactions [2][3][4]. Although there are many reports on alkyne transformations, one recent development in this area has been the reaction of alkynes with tertiary alkyl electrophiles to produce functionalizedquaternarycarbon atoms via addition [5][6][7][8][9][10] or coupling [11][12][13